ISSN 1662-4009 (online)

ey0017.7-13 | Basic Science | ESPEYB17

7.13. Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan

B Hollis , FR Day , AS Busch , DJ Thompson , ALG Soares , PRHJ Timmers , A Kwong , DF Easton , PK Joshi , NJ; PRACTICAL Consortium; 23andMe Research Team Timpson , KK Ong , JRB Perry

To read the full abstract: Nature communications vol. 11,1 1536. 24 Mar. 2020. doi: https://www.nature.com/articles/s41467-020-14451-5This multi-trait genome-wide association study (GWAS) for male puberty timing identifies 76 independent signals for puberty timing and highlights relationships with natural hair colour and lifespan. The timing of puber...

ey0017.15-15 | (1) | ESPEYB17

15.15. Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior

A Ganna , KJH Verweij , MG Nivard , R Maier , R Wedow , AS Busch , A Abdellaoui , S Guo , JF Sathirapongsasuti , 23andMe Research Team , P Lichtenstein , S Lundstrom , N Langstrom , A Auton , KM Harris , GW Beecham , ER Martin , AR Sanders , JRB Perry , BM Neale , BP Zietsch

To read the full abstract: Science 2019;365:eaat7693.These authors performed a genome-wide association study on 493 001 participants of European-ancestry from the USA, UK, and Sweden to identify genes associated with sexual orientation. They found multiple loci implicated in same-sex sexual behavior indicating that, like other behavioral traits, non-heterosexual behavior is polygenic.As many as 4% to 10% of US individuals ...